http://lcni-3.uoregon.edu/phenowiki/index.php?title=PMID_14643087&feed=atom&action=historyPMID 14643087 - Revision history2024-03-28T11:15:15ZRevision history for this page on the wikiMediaWiki 1.26.2http://lcni-3.uoregon.edu/phenowiki/index.php?title=PMID_14643087&diff=570&oldid=prevJaredfox: New page: {| class="wikitable" style="width:100%; height:30px" border="1" "text-align:center" |- ! style="background:#ffffcc; width:50px" | Main Page !! style="background:#ffffcc; width:50px"...2007-11-28T22:52:41Z<p>New page: {| class="wikitable" style="width:100%; height:30px" border="1" "text-align:center" |- ! style="background:#ffffcc; width:50px" | <a href="/phenowiki/index.php/Main_Page" title="Main Page">Main Page</a> !! style="background:#ffffcc; width:50px"...</p>
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<big> '''PMID 14643087''' </big><br />
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[[Image:PW1_v1.jpg | frame |right | INSERT IMAGE from PAPER here ]]<br />
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* Title<br />
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''Do schizotypal symptoms mediate the relationship between genetic risk for schizophrenia and impaired neuropsychological performance in co-twins of schizophrenic patients?''<br />
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* Authors<br />
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''Johnson JK, Tuulio-Henriksson A, Pirkola T, Huttunen MO, Lönnqvist J, Kaprio J, Cannon TD''<br />
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* Year<br />
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''2003''<br />
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* Abstract<br />
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''BACKGROUND: Neurocognitive deficits and symptoms of schizotypal personality disorder are both elevated in the first-degree relatives of schizophrenic patients, but their relationship to each other and their potential common genetic source remain unclear. METHODS: Fifty unaffected co-twins of schizophrenic patients and 123 control twins were assessed with a neuropsychological battery and structured clinical interviews. RESULTS: Working memory was influenced by genetic risk for schizophrenia but not schizotypal symptoms. Nearly all other domains were influenced by schizotypy symptoms but only in the co-twins of schizophrenic patients. Schizotypy symptoms in the absence of a family history did not seem to be related to impaired neurocognitive functioning. CONCLUSIONS: Schizotypy symptoms in those with genetic risk for schizophrenia are associated with increased risk for cognitive deficits. Some neurocognitive deficits might covary with subpsychotic symptoms due to a shared genetic factor. Community-ascertained schizotypal individuals might not be appropriate for modeling underlying genetic risk for schizophrenia.''<br />
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* Keywords<br />
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''Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Neuropsychological Tests, Schizophrenia, Schizophrenic Psychology, Schizotypal Personality Disorder, Social Adjustment, Twins, Dizygotic, Twins, Monozygotic''<br />
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* Reference<br />
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* Input Author<br />
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* Notes<br />
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* Closely related pages (vote or nominate related pages)<br />
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* Links out: <br />
**[http://www.google.com/search?hl=en&q=PMID+14643087 Google 14643087]<br />
**[http://en.wikipedia.org/wiki/PMID_14643087 Wikipedia 14643087]<br />
**[http://www.pubbrain.org/ PubBrain]<br />
**PMID 14643087<br />
**-coming soon...ucla cognitive atlas-<br />
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* Database links<br />
** [http://128.97.131.250/phenowiki/search.php?action=search&condition_contrast=nonesel&condition_contrast=nonesel&cognitive_domain=nonesel&task=nonesel&sample=nonesel&sample_type=nonesel&expandedview=yes&pubmedid=14643087 Phenowiki Records For 14643087]</div>Jaredfox